Our group studies how molecular interactions shape the structure, mechanics, and function of biological membranes, with a particular focus on organelle membranes. We combine theoretical biophysics with multiscale computer simulations to understand how these membranes acquire their complex shapes and how their architecture supports biological function.

Research themes

Organelle membrane architecture

How do interactions between lipids and proteins generate and maintain the distinctive shapes of organelle membranes? We investigate the physical principles connecting membrane composition and mechanics to organelle structure and function.

Membrane organisation and remodelling

We explore how membrane curvature, composition, and protein–lipid interactions act together to organise membranes and drive changes in their shape.

Connecting molecular and cellular scales

We develop computational methods that link molecular models of lipids and proteins to mesoscale and continuum descriptions of membrane shape and dynamics. These approaches allow us to investigate how local molecular interactions give rise to large-scale membrane behaviour.